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Other nanotechnology standards are published by ISO. They still cover valuable information on situations that can arise from working with nanomaterials. These include highly specific material testing on certain chemistries, quality assessment on certain nanostructures, risk management regarding certain chemistries, and more. Other nanotechnology standards are invaluable if your laboratory or organization works with the topics listed below and can protect valuable investments.

ISO/TR 19601:2017

Nanotechnologies - Aerosol generation for air exposure studies of nano-objects and their aggregates and agglomerates (NOAA)

ISO/TR 19601:2017 describes methods for producing aerosols of nano-objects and their aggregates and agglomerates (NOAA) for in vivo and in vitro air exposure studies. The purpose of ISO/TR 19601:2017 is to aid in selecting an appropriate aerosol generator to fulfil a proposed toxicology study design. ISO/TR 19601:2017 describes characteristics of aerosol generation methods, including their advantages and limitations. ISO/TR 19601:2017 does not provide guidance for aerosolization of specific nano-objects.

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ISO/TS 16550:2014

Nanotechnologies - Determination of silver nanoparticles potency by release of muramic acid from Staphylococcus aureus

ISO/TS 16550:2014 provides a test method for evaluating potency of silver nanoparticles to cell wall degradation of Staphylococcus aureus and muramic acid release as quantified by a gas chromatography-mass spectrometry (GC-MS).

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ISO/TS 13830:2013

Nanotechnologies - Guidance on voluntary labelling for consumer products containing manufactured nano-objects

ISO/TS 13830:2013 provides guidance on the content of voluntary labels for consumer products containing manufactured nano-objects.

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ISO/TR 11811:2012

Nanotechnologies - Guidance on methods for nano- and microtribology measurements

ISO/TR 11811:2012 establishes techniques for the evaluation of tribological performance of sliding contacts with a lateral size of between a few nanometres and 10 µm, and where the applied load is between 50 µN and 100 mN. It describes procedures for undertaking these measurements, and provides guidance on the effect of parameters on test results. It does not cover existing SPM techniques, such as frictional force microscopy and atomic force microscopy (AFM).

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ISO/TS 13278:2017

Nanotechnologies - Determination of elemental impurities in samples of carbon nanotubes using inductively coupled plasma mass spectrometry

ISO/TS 13278:2017 provides methods for the determination of residual elements other than carbon in samples of single-wall carbon nanotubes (SWCNTs) and multiwall carbon nanotubes (MWCNTs) using inductively coupled plasma mass spectrometry (ICP-MS). The purpose of this document is to provide optimized digestion and preparation procedures for SWCNT and MWCNT samples in order to enable accurate and quantitative determinations of elemental impurities using ICP-MS.

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ISO 29701:2010

Nanotechnologies - Endotoxin test on nanomaterial samples for in vitro systems - Limulus amebocyte lysate (LAL) test

ISO 29701:2010 describes the application of a test using Limulus amebocyte lysate (LAL) reagent for the evaluation of nanomaterials intended for cell-based in vitro biological test systems. The test is suitable for use with nanomaterial samples dispersed in aqueous media, e.g. water, serum or reaction medium, and to such media incubated with nanomaterials for an appropriate duration at 37 °C. ISO 29701:2010 is restricted to test samples for in vitro systems, but the methods can also be adapted to nanomaterials to be administered to animals by parenteral routes.

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