Historical
CLSI MM18-A
Interpretive Criteria for Identification of Bacteria and Fungi by DNA Target Sequencing; Approved Guideline
The information presented in this document is intended for use with molecular diagnostic testing procedures published in the following CLSI approved guidelines: MM3-A2-Molecular Diagnostic Methods for Infectious Diseases: Approved Guideline- Second Edition; MM9-A-Nucleic Acid Sequencing Methods in Diagnostic Laboratory Medicine: Approved Guideline. The guidelines contain information about the development, evaluation, and application of nucleic acid-based testing for infectious diseases and chemistries for diagnostic laboratories.
Laboratories often receive clinical isolates for bacterial and fungal identification that have ambiguous biochemical profiles by conventional testing. The identification of microorganisms historically has relied on phenotypic methods. Because of the growing microbial diversity with emergence of common pathogens having rare or unique phenotypic characteristics and new pathogenic microorganisms with poorly defined phenotypes, conventional methods often cannot fully characterize bacterial or fungal isolates, and laboratories are now relying on broad-range DNA sequencing for microorganism identification. The informationhere represents the most current information.
Clinical And Laboratory Standards Institute [clsi]